Synthetic drugs can be produced using a number of different production techniques, involving a range of different chemical precursor substances. The precursors needed to make amphetamine and methamphetamine overlap significantly, but are distinct from the precursors used to make MDMA. In Europe, and indeed globally, amphetamine is most frequently synthesised from benzyl methyl ketone (BMK). To make methamphetamine, although BMK may also be used, ephedrine and pseudoephedrine are more common. MDMA is primarily produced from piperonyl methyl ketone (PMK), which can also be produced from safrole (or oils rich in safrole) and piperonal.